The company said the partnership will focus on the discovery and development of novel immunostimulatory antibody-drug conjugates. Google Map Sutro Biopharma, Inc. (NASDAQ: STRO), a clinical-stage oncology company, announced its strategic collaboration and licensing agreement with Astellas Pharma We examined the poten Scientist. "We are pleased with the . Sutro Biopharma Inc's trailing 12-month revenue is $53.2 million with a -252.3% profit margin. Sutro Biopharma, Inc., headquartered in South San Francisco, is a clinical-stage oncology company pioneering site-specific and novel-format antibody drug conjugates (ADCs). The stock was in 9 hedge funds' portfolios at the end . ADC Review | J. Antibody-drug Conjugates. Given broad expression of CD74 in leukemias, we evaluated the efficacy of STRO-001 in AML and ALL preclinical models. Sutro Biopharma has been granted FDA Fast Track Designation for STRO-002, a folate receptor alpha-targeting antibody drug conjugate indicated for the treatment of patients with platinum-resistant epithelial ovarian, fallopian tube, or primary peritoneal cancer who have received 1 to 3 prior lines of systemic therapy. Shamim AHMAD, Senior Scientist | Cited by 641 | of Sutro Biopharma, Inc., California (SUTROBIO) | Read 39 publications | Contact Shamim AHMAD High expression of CD74 has been confirmed in follicular lymphoma, diffuse large B-cell lymphoma (DLBCL), chronic lymphocytic leukemia (CLL)/small lymphocytic lymphoma (SLL) and other types of NHL with immunohistochemistry (IHC) using the LL1 antibody (Stein et al. Sutro's proprietary and integrated cell-free protein synthesis and site-specific conjugation platforms led to the discovery of Sutro's first two internally-developed ADCs. SOUTH SAN FRANCISCO, Calif., Dec. 7, 2020 - Sutro Biopharma, Inc. (NASDAQ: STRO), a clinical-stage drug discovery, development and manufacturing company focused on the application of precise protein engineering and rational design to create next-generation cancer and autoimmune therapeutics, today announced a poster presentation at the virtual 62ndAmerican Society of Hematology (ASH) Annual . In vivo efficacy of STRO-002 was evaluated in MV4;11 FOLR1+ NSG xenograft models, which showed potent activity that led to complete leukemia clearance after 3 weekly doses of STRO-002 at 2.5 and 5 mg/kg ( Figure 1F ). Sutro Biopharma, Inc. (NASDAQ: STRO), a clinical-stage drug discovery, development and manufacturing company focused on the application of precise protein engineering and rational design to create . As of September 30, 2022, Sutro Biopharma Inc had a $283.2 million market capitalization, putting it in the 46th percentile of companies in the Biotechnology & Medical Research industry. south san francisco, calif., nov. 10, 2021 /prnewswire/ -- sutro biopharma, inc. (nasdaq: stro ), a clinical-stage drug discovery, development and manufacturing company focused on the application. 111 Oyster Point Blvd South San Francisco, CA 94080 Phone: 650-881-6500 Fax: 650-553-9659. Dr. Trevor Hallam has more than 25 years of experience in pharmaceutical discovery and development. News release. The partnership will enable Astellas and . 111 Oyster Point Blvd South San Francisco, CA 94080 Phone: 650-881-6500 Fax: 650-553-9659. Selected Balance Sheet Financial Data (Unaudited) south san francisco, calif., july 26, 2022 (globe newswire) -- sutro biopharma, inc. ("sutro" or the "company") (nasdaq: stro), a clinical-stage oncology company pioneering site-specific and novel-format antibody drug conjugates (adcs), today announced that the first patient has been dosed in a phase 1 study of an investigational candidate Selected Statements of Operations Financial Data (Unaudited) (In thousands, except per share amounts) Sutro Biopharma, Inc. south san francisco, calif., march 22, 2021 /prnewswire/ -- sutro biopharma, inc. (nasdaq: stro), a clinical-stage drug discovery, development and manufacturing company focused on the application of precise protein engineering and rational design to create next-generation cancer and autoimmune therapeutics, today announced the strengthening of Introduction: STRO-001 is a novel CD74-targeting ADC comprised of an anti-CD74 human IgG1 antibody (SP7219) genetically incorporating the non-natural amino acid para-azidomethyl-L-phenylalanine (pAMF) with a non-cleavable dibenzocyclooctyne (DBCO)-maytansinoid linker-warhead. Sutro Biopharma, Inc., located in South San Francisco, is a clinical-stage drug discovery, development and manufacturing company. Sutro Biopharma to Present at the 2022 Wedbush PacGrow Healthcare Conference Using precise protein engineering and rational design, Sutro is . Sutro Biopharma (650) 801-5728 ajchang@sutrobio.com Media Contact Maggie Beller Russo Partners (646) 942-5631 Maggie.beller@russopartnersllc.com Sutro Biopharma, Inc. Sutro Biopharma, Inc. Research South San Francisco, United States Position Vice President July 2006 - July 2012 OncoMed Pharmaceuticals Molecular/Cellular Biology Redwood City, United States. These forward-looking statements speak only as of the date of this press release, and Sutro undertakes no obligation to revise or update any forward-looking statements to reflect events or circumstances after the date hereof. Fenwick represented Sutro Biopharma, Inc. (NASDAQ: STRO), a clinical-stage oncology company, in its strategic collaboration and licensing agreement with Astellas Pharma Inc. (TSE: 4503), a pharmaceutical company conducting business in more than 70 countries around the world. Using precise protein engineering and rational design, Sutro is . South San Francisco-based clinical-stage biotechnology company Sutro Biopharma has received a milestone payment under its collaboration and license agreement with the healthcare division of Merck KGaA, Darmstadt, Germany.. Clin Cancer Res 2007). Sutro Biopharma, Inc., headquartered in South San Francisco, is a clinical-stage oncology company pioneering site-specific and novel-format antibody drug conjugates (ADCs). Google Map Inventors: Sushmita Mimi Roy, Sunil Bajad, Evan Green, Henry Heinsohn EXPRESSION OF BIOLOGICALLY ACTIVE PROTEINS IN A BACTERIAL CELL-FREE SYNTHESIS SYSTEM USING BACTERIAL CELLS TRANSFORMED TO EXHIBIT ELEVATED LEVELS OF CHAPERONE EXPRESSION. CD74 is a type II transmembrane glycoprotein involved in the formation and transport of MHC class II protein. south san francisco, calif., feb. 28, 2022 /prnewswire/ -- sutro biopharma, inc. ("sutro" or the "company") (nasdaq: stro), a clinical-stage drug discovery, development and manufacturing company focused on the application of precise protein engineering and rational design to create next-generation cancer therapeutics, today reported its financial Sutro has two wholly owned ADCs in the clinicSTRO-002, a folate receptor alpha (FolRa)-targeting ADC, in clinical studies for ovarian and endometrial cancers; and STRO-001 . Sutro Biopharma, Inc., located in South San Francisco, is a clinical-stage drug discovery, development and manufacturing company. Using precise protein engineering and rational design, Sutro is . Sutro Biopharma Partnership since August 2018 In August 2018, LLS partnered with Sutro Biopharma to support "A Phase 1 Open-Label, Safety, Pharmacokinetic and Preliminary Efficacy Study of STRO-001, an Anti-CD74 Antibody Drug Conjugate, in Patients With Advanced B-Cell Malignancies." Sutro Biopharma and the biopharmaceutical division of Merck KGaA, Darmstadt, Germany, which operates as EMD Serono in the United States and Canada, have signed collaboration and license agreement to develop antibody drug conjugates (ADCs). Our focus is aimed primarily on next-generation cancer therapeutics - antibody drug conjugates, bispecific antibodies and cytokine derivatives. Sutro Biopharma Inc. shares rose 24% to $5.36 after the company said it entered into a worldwide strategic collaboration and licensing agreement with Astellas Pharma Inc. STRO-001 (Sutro Biopharma) is a CD74-directed, site-specific ADC developed for the treatment of multiple myeloma and lymphomas. Sutro Biopharma, Inc.; January 5, 2022. Sutro Biopharma. Sutro Biopharma, Inc. San Francisco, California, United States Overview Members (35) Recent publications Cell-free technologies for biopharmaceutical research and production New Literature Review. Sutro Biopharma, Inc., located in South San Francisco, is a clinical-stage drug discovery, development and manufacturing company. South San Francisco-based clinical-stage biotechnology company Sutro Biopharma has received a milestone payment under its collaboration and license agreement with the healthcare division of Merck KGaA, Darmstadt, Germany.. Investor & Media Contact Annie J. Chang Sutro Biopharma (650) 801-5728 ajchang@sutrobio.com Amy Bonanno Solebury Trout Resources for For Clinicians; Drug Map (ADC) Peer Review Articles; The Review; . Publications. Sutro Biopharma announces interim data from dose-expansion cohort of STRO-002 phase 1 study for patients with advanced ovarian cancer. Sutro Biopharma, Inc. ClinicalTrials.gov Identifier: NCT05200364 Other Study ID Numbers: STRO-002-GM2 : First Posted: January 20, 2022 Key Record Dates: Last Update Posted: August 2, 2022 Last Verified: August 2022 Using precise protein engineering and rational design, Sutro is . Selected Balance Sheets Financial Data (Unaudited) The collaboration will focus on the discovery and development of novel . Clinical evaluations and/or laboratory tests will be performed at a pre-specified schedule-weekly for cycles 1-4, and at the beginning of every cycle starting with cycle 5 as described in the schedule of assessments. SUTRO BIOPHARMA, INC. Management's Discussion and Analysis of Financial Condition and Results of Operations (form 10-K) 02/28/2022 | 05:17pm EDT The following discussion should be read in conjunction with the attached financial statements and notes thereto. He joined Sutro Biopharma as CSO in late 2010. Sutro Biopharma, Inc. | SUTROBIO Connect with experts in your field Join ResearchGate to contact this researcher and connect with your scientific community. Sutro Biopharma, Inc., located in South San Francisco, is a clinical-stage drug discovery, development and manufacturing company. - Responsible for developing, optimizing, qualifying and validating a broad range of potency assays like antigen binding . The anti-leukemia effects of STRO-002 resulted in significant increase in survival (p=0.002, Figure 1G ). The average salary for Communications Editor Supervisor at companies like SUTRO BIOPHARMA INC in the United States is $119,461 as of September 26, 2022, but the range typically falls between $109,277 and $134,909. The novel agent is being developed for the treatment of adult patients with metastatic solid tumors, including non-small cell lung cancer (NSCLC) and esophageal squamous . The novel agent is being developed for the treatment of adult patients with metastatic solid tumors, including non-small cell lung cancer (NSCLC) and esophageal squamous . Folate Receptor Alpha-targeting Antibody-drug Conjugate gets FDA Fast Track Designation. SOUTH SAN FRANCISCO, Sept. 21, 2020 /PRNewswire/ -- Sutro Biopharma, Inc. (NASDAQ: STRO), a clinical-stage drug discovery, development and manufacturing company today announced that it has been recognized as Best New Drug Developer at the World ADC Digital Awards, held during the World ADC Digital Event. Follow Sutro on Twitter, @Sutrobio, and at www.sutrobio.com to learn more about our passion for changing the future of oncology. The milestone was achieved upon the designation by Merck KGaA of an undisclosed bispecific antibody-drug conjugate as a clinical development candidate with approval to advance to IND-enabling . Sutro Biopharma is a biopharmaceutical company that uses its patented OCFS protein synthesis technology to develop next-generation protein therapeutics for the treatment of human disease. Sutro Biopharma, Inc. is looking for An Associate Director of Upstream Process Development who will join the Cell-Free Group in developing processes using Sutro's novel cell-free protein synthesis process (XpressCF) to manufacture protein biotherapeutics. STRO-001 is a novel antibody drug conjugate (ADC) comprised of a human aglycosylated anti-CD74 IgG1 antibody (SP7219) genetically incorporating the non-natural amino acid para-azidomethy-L-phenyalanine (pAMF) to enable the site-specific conjugation of a non-cleavable maytansinoid linker-warhead. Assignee: Sutro Biopharma, Inc. President, Research & Chief Scientific Officer Sutro Biopharma, Inc. Apr 2021 - Present1 year 3 months Publications A simplified and robust protocol for immunoglobulin expression in Escherichia. Using precise protein engineering and rational design, Sutro is . Coming of Age: Antibody-drug Conjugates, Highly Targeted Anti . Since then Dr. Hallam has shaped Sutro's biochemical synthesis technology to generate a disruptive discovery and manufacturing platform for novel best-in-class bispecific and antibody-drug conjugate protein therapeutics. Apr 2017 - Present5 years 4 months. Liked by Daniel Calarese. Publication number: 20140315245 . Sutro Biopharma. Sutro Biopharma (650) 801-5728 ajchang@sutrobio.com Media Contact Amy Bonanno Solebury Trout (914) 450-0349 abonanno@soleburytrout.com Sutro Biopharma, Inc. Sutro Biopharma, Inc., headquartered in South San Francisco, is a clinical-stage oncology company pioneering site-specific and novel-format ntibody drug conjugates (ADCs). Investor Contact Annie J. Chang Sutro Biopharma (650) 801-5728 ajchang@sutrobio.com Media Contact Amy Bonanno Solebury Trout (914) 450-0349 abonanno@soleburytrout.com [ Back To TMCnet.com's Homepage ] The funding will support Phase 1 clinical testing for two products intended to treat ovarian and endometrial cancer and multiple myeloma. 19 Publications 2,083 Reads 842 Citations Introduction Skills and Expertise Apoptosis Cancer Biology Cell Culture Cell Signaling Cancer Biomarkers Cancer Cell Biology Flow Cytometry. Fenwick represented Sutro Biopharma, Inc. on the deal. Sutro Biopharma Reports Second Quarter 2022 Financial Results, Business Highlights and Anticipated Milestones - Collaboration with Astellas on discovery and development of iADCs for up to three targets, includes an upfront payment of $90 million and $422.5. SOUTH SAN FRANCISCO, Calif., July 12, 2022 - Sutro Biopharma, Inc. ("Sutro" or the "Company") (NASDAQ: STRO), a clinical-stage oncology company pioneering site-specific and novel-format antibody drug conjugates (ADCs), today announced that management will host a. read more Sutro Biopharma, Inc., located in South San Francisco, is a clinical-stage drug discovery, development and manufacturing company. Google Map 111 Oyster Point Blvd South San Francisco, CA 94080 Phone: 650-881-6500 Fax: 650-553-9659. Sutro has two wholly owned ADCs in the clinicSTRO-002, a folate receptor alpha (FolRa)-targeting ADC, in clinical studies for ovarian and endometrial cancers; and STRO . Gang YIN, Principal Scientist | Cited by 1,345 | of Sutro Biopharma, Inc., California (SUTROBIO) | Read 44 publications | Contact Gang YIN Sutro is applying its technology to the development of next-generation, non-native protein structures such as antibody fragments, single-chain antibodies, and other proteins with novel scaffolds. Join for free Log in Publications About. Salary ranges can vary widely depending on many important factors, including education, certifications, additional skills, the . Prior to Sutro, Dr. Hallam . Selected Statements of Operations Financial Data (Unaudited) (In thousands, except share and per share amounts) Sutro Biopharma, Inc. Study drug, STRO-002, is administered by intravenous (IV) infusion on day 1 of 21-day cycles. Currently, Sutro Biopharma Inc's price-earnings ratio is . will be required to make presentations to internal teams and senior management and . Alexander STEINER | Cited by 1,114 | of Sutro Biopharma, Inc., California (SUTROBIO) | Read 26 publications | Contact Alexander STEINER San Francisco Bay Area. Sutro Biopharma has achieved a milestone under its collaboration and license agreement with the healthcare division of Merck KGaA, Darmstadt, Germany, in the United Stated and Canada known as EMD Serono.. Danielle Garcia-August 18, 2021. Tag: Sutro Biopharma. STRO-001 is a site-specific, predominantly single-species, fully human, aglycosylated anti-CD74 antibody-drug conjugate incorporating a non-cleavable linker-maytansinoid warhead with a drug-antibody ratio of 2 which was produced by a novel cell-free antibody synthesis platform. Sutro Biopharma, Inc. (NASDAQ:STRO) shares haven't seen a lot of action during the first quarter. south san francisco, calif., dec. 11, 2020 - sutro biopharma, inc. (nasdaq: stro), a clinical-stage drug discovery, development and manufacturing company focused on the application of precise protein engineering and rational design to create next-generation cancer and autoimmune therapeutics, today announced the closing of its upsized public For more info, https://lnkd.in/eHsB_XJ #Merck. SOUTH SAN FRANCISCO, Calif., Sept. 17, 2021 /PRNewswire/ -- Sutro Biopharma, Inc. (NASDAQ: STRO), a clinical-stage drug discovery, development and manufacturing company focused on the application of precise protein engineering and rational design to create next-generation cancer and autoimmune therapeutics, today announced that on September 15, 2021, the Compensation Committee of Sutro's Board . Using precise protein engineering and rational design, Sutro is advancing next-generation oncology therapeutics. "We are honored to receive the World ADC Best New Drug Developer Award," said Bill Newell . . Director, Upstream Process Development (South San Francisco, CA) Sutro Biopharma, Inc. is looking for a technical leader who will report to the Senior Director of Upstream Process Development. Sutro Biopharma, Inc. Earns Milestone Payment from Cytokine Derivatives Collaboration with Merck. Sutro Biopharma is a clinical stage company pioneering a compelling and unique way of discovering, developing and manufacturing therapeutics. Sutro has two wholly owned ADCs in the clinicSTRO-002, a folate receptor alpha (FolRa)-targeting ADC, in clinical studies for ovarian and endometrial cancers; and STRO . Sutro Biopharma Inc. Company Profile - The Business Journals Sutro Biopharma Inc. South San Francisco, CA Overview Industry biotechnology Revenue $61.9M Employees 255 Contact sutrobio.com. Bay Area oncology company Sutro Biopharma received a second investment from Amgen Ventures as part of an $85 million Series E funding round. Sutro Biopharma, Inc., located in South San Francisco, is a clinical-stage drug discovery, development and manufacturing company. 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